Basic Information
VIS ID
TVIS10018841
Fusion event
HBV-chr4 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1818
Integrated sequence
GTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATG| |CAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTT
Host Sequence
Chromosome
chr4
Cytoband
q13.3
Reference genome
GRCh37.55
Start
74372486/73506769 (Hg38)
End
74372486/73506769 (Hg38)
Nearest miRNA
hsa-mir-12113/Upstream/7229841; hsa-mir-1243/Downstream/3066799;
Nearest TSS
ENST00000502981/Upstream/11654; ENST00000502291/Downstream/2034;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/247356, chr4-CpG: 20/Downstream/113558
Nearby gene
LINC02499
Upstream sequence
TAAAATTGCCCTTTATGGCCTGACAGTAACTTTTTTTTATTCATTTGGGGACAACTATGTCCGTGAGCTTCCGTCCAGAGATTATAGTAGTAAATTGTAA
Downstream sequence
tagcagtgtctgcggtgggtaACAGTCTTGGAGCATTCTTCCAAAGGATTTGACAAAAGATTGGACTTAGTTTAATAGGTACATTTTTGATAGTTCTAAG
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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