ZNF300 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10018842
Fusion event
HBV-ZNF300 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
2579
Integrated sequence
AACTTTACTGGGCTTTATTCTTCTACTGTACCTGTCTTTAATCCTCATTGGAAAACACCATCTTTTCCTAATATACATTTACACCAAGACATTATCAAAA| |AATGTGAACAGTTTGTAGGCCCACTCACAGTTAATGAGAAAAGAAGATTGCAATTGATTATGCCTGCCAGGTTTTATCCAAAGGTTACCAAATATTTACC
Host Sequence
Chromosome
chr5
Cytoband
q33.1
Reference genome
GRCh37.55
Start
150279031/150899469 (Hg38)
End
150279031/150899469 (Hg38)
Location type
Intron3
Target gene
ZNF300
miRNAs that regulate target gene
hsa-mir-155-5p
Nearest miRNA
hsa-mir-10397/Upstream/1166579; hsa-mir-103a-1/Downstream/622618;
Nearest TSS
ENST00000502646/Upstream/50972; ENST00000625178/Downstream/5320;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/120377, chr5-CpG: 23/Downstream/5354
Upstream sequence
tagccatgtgacaaagttctggccagtgcgatgtaagcagaaatactgtgtgagaggtatgggaaaatctttttgagagggcacatcctttttcctttca
Downstream sequence
aagatcattaatctaatctctttatttcataggaaaatgatcttagcttcccccaaatgtaatagctttcttatatacatacaatagttagtaatagaAT
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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