Basic Information
VIS ID
TVIS10018844
Fusion event
HBV-FLJ39630 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
2473
Integrated sequence
AGAAGAACTCCCTCGCCTCGCAGACGAAGGTCTCAATCGCCGCGTCGCAGAAGATCTCAATCTCGGGAATCTCAATGTTAGTATTCCTTGGACTCATAAG| |GTGGGGAACTTTACTGGGCTTTATTCTTCTACTGTACCTGTCTTTAATCCTCATTGGAAAACACCATCTTTTCCTAATATACATTTACACCAAGACATTA
Host Sequence
Chromosome
chr8
Cytoband
q12.3
Reference genome
GRCh37.55
Start
63679968/62767409 (Hg38)
End
63679968/62767409 (Hg38)
Location type
Intron4
Target gene
FLJ39630
Nearest miRNA
hsa-mir-124-1/Upstream/1052550; hsa-mir-10400/Downstream/1611740;
Nearest TSS
ENST00000518652/Upstream/293140; ENST00000622794/Downstream/210452;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/517904, chr8-CpG: 91/Downstream/271154
Upstream sequence
AAAGCAAAGTATTTTCTAACTACTTGGTAATTTACAACATAACTTTTTCTTCCTTTGAAGGCAGTAGATTTCATTATTATGCAGAGTAATATTACATTCC
Downstream sequence
cctacaagagaggaaagcagggctgtaaaacagagagacacacgcagatacagacaggcagacagaggatccagttatgctcaacccagctctacccttg
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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