Basic Information
VIS ID
TVIS10018846
Fusion event
HBV-chr9 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1755
Integrated sequence
ATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGAT| |TAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCAT
Host Sequence
Chromosome
chr9
Cytoband
q33.1
Reference genome
GRCh37.55
Start
121119833/118357555 (Hg38)
End
121119833/118357555 (Hg38)
Nearest miRNA
hsa-let-7a-1/Upstream/4148026; hsa-mir-12126/Downstream/1887424;
Nearest TSS
ENST00000422679/Upstream/460299; ENST00000456032/Downstream/348405;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/612191, chr9-CpG: 97/Downstream/1011253
Nearby gene
TLR4
Upstream sequence
TCCACTAGTGTTTTAGTTTTTTCTTAAAATCATCTGTTAGTCTAGGAATCTGTTCTCAAAAGTGCATTGTTgggggtatagcttagtggtagagcattta
Downstream sequence
TAGGGAGGGGCAGACCAGCAGcactgaccaagtgttgactgtgtacccattatcaggctgggcacttgatatgcgccatctcatttaattttcactaaaa
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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