VISDB Viral Integration Site DataBase

VIS ID

TVIS10018847

Fusion event

HBV-chr10 integration

Validated

No

Detection method

VirusFinder

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Good

Reported year

2017

PubMed ID

Virus name

HBV

Reference genome

Start

1806

Integrated sequence

ACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGC| |ACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGG

Chromosome

chr10

Cytoband

p12.2

Reference genome

Start

End

22619403/22330474 (Hg38)

Location type

Exon

Target gene

BMI1 ; COMMD3-BMI1

miRNAs that regulate target gene

hsa-mir-200c-3p ; hsa-mir-16-5p ; hsa-mir-15a-5p ; hsa-mir-128-3p ; hsa-mir-302b-3p ; hsa-mir-203a-3p ; hsa-mir-708-5p ; hsa-mir-200b-3p ; hsa-mir-194-5p ; hsa-mir-218-5p ; hsa-let-7g-5p ; hsa-mir-33a-5p ; hsa-mir-106b-3p ; hsa-mir-27a-3p ; hsa-mir-544a ; hsa-mir-494-3p ; hsa-mir-495-3p ; hsa-mir-300 ; hsa-mir-30e-5p ; hsa-mir-302a-3p ; hsa-mir-183-5p ; hsa-mir-379-3p ; hsa-mir-380-3p ; hsa-mir-411-3p ; hsa-mir-4495 ; hsa-mir-379-3p ; hsa-mir-380-3p ; hsa-mir-411-3p ; hsa-mir-4495 ; hsa-mir-559 ; hsa-mir-548b-5p ; hsa-mir-548a-5p ; hsa-mir-548c-5p ; hsa-mir-548d-5p ; hsa-mir-548j-5p ; hsa-mir-548n ; hsa-mir-548h-5p ; hsa-mir-548i ; hsa-mir-548w ; hsa-mir-548y ; hsa-mir-548o-5p ; hsa-mir-548ab ; hsa-mir-548ad-5p ; hsa-mir-548ae-5p ; hsa-mir-548ak ; hsa-mir-548am-5p ; hsa-mir-548ap-5p ; hsa-mir-548aq-5p ; hsa-mir-548ar-5p ; hsa-mir-548as-5p ; hsa-mir-548au-5p ; hsa-mir-548ay-5p ; hsa-mir-548bb-5p ; hsa-mir-559 ; hsa-mir-548b-5p ; hsa-mir-548a-5p ; hsa-mir-548c-5p ; hsa-mir-548d-5p ; hsa-mir-548j-5p ; hsa-mir-548n ; hsa-mir-548h-5p ; hsa-mir-548i ; hsa-mir-548w ; hsa-mir-548y ; hsa-mir-548o-5p ; hsa-mir-548ab ; hsa-mir-548ad-5p ; hsa-mir-548ae-5p ; hsa-mir-548ak ; hsa-mir-548am-5p ; hsa-mir-548ap-5p ; hsa-mir-548aq-5p ; hsa-mir-548ar-5p ; hsa-mir-548as-5p ; hsa-mir-548au-5p ; hsa-mir-548ay-5p ; hsa-mir-548bb-5p ; hsa-mir-580-5p ; hsa-mir-3120-3p ; hsa-mir-3942-5p ; hsa-mir-4703-5p ; hsa-mir-580-5p ; hsa-mir-3120-3p ; hsa-mir-3942-5p ; hsa-mir-4703-5p ; hsa-mir-376c-3p ; hsa-mir-320a ; hsa-mir-586 ; hsa-mir-586 ; hsa-mir-452-5p ; hsa-mir-487b-3p ; hsa-mir-548t-5p ; hsa-mir-548az-5p ; hsa-mir-548t-5p ; hsa-mir-548az-5p ; hsa-mir-195-3p ; hsa-mir-153-5p ; hsa-mir-16-2-3p ; hsa-mir-4666a-3p ; hsa-mir-338-5p ; hsa-mir-153-5p ; hsa-mir-195-3p ; hsa-mir-16-2-3p ; hsa-mir-4666a-3p ; hsa-mir-338-5p ; hsa-mir-15a-3p ; hsa-mir-192-5p ; hsa-mir-21-5p ; hsa-mir-3622b-5p ; hsa-mir-200c-5p ; hsa-mir-128-1-5p

Nearest miRNA

hsa-mir-1265/Upstream/833828; hsa-mir-107/Downstream/1945211;

Nearest TSS

Nearest CpG islands

None/Target, chr10-CpG: 68/Upstream/4464, chr10-CpG: 225/Downstream/3947

Nearest cancer related gene

BMI1(OG, No orient, 0)

Upstream sequence

TTAATTACAGAAGGAAGAAAAAATCTATTAAGCAACAGCACAATAATAGACATCCCCCAAAATGACCATAATCCCCAAATTAAAAAGGATCCAGACAATT

Downstream sequence

TATACTTTTCTCCAGTAATACATGTTTACTTTAAAGATTGTTGCAGTGAAGAAAAACCTTTAACTGAGAAATATGGAAACCGTCTTAATTTTCCATTGGC

Target sequence

CTTTA