hsa-mir-4659a-3p _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10018849
Fusion event
HBV-chr14 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1809
Integrated sequence
TCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACC| |AGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACA
Host Sequence
Chromosome
chr14
Cytoband
q13.2
Reference genome
GRCh37.55
Start
36179875/35710669 (Hg38)
End
36179875/35710669 (Hg38)
Location type
Intron
Target gene
RALGAPA1 ; RALGAPA1P1
miRNAs that regulate target gene
hsa-mir-17-5p ; hsa-mir-4659b-3p ; hsa-mir-4659a-3p ; hsa-mir-6875-3p ; hsa-mir-6868-3p ; hsa-mir-2355-5p ; hsa-mir-361-5p ; hsa-mir-627-3p ; hsa-mir-4778-3p ; hsa-mir-1248 ; hsa-mir-1237-3p ; hsa-mir-2115-3p ; hsa-mir-3074-3p ; hsa-mir-4282
Nearest miRNA
hsa-mir-208a/Upstream/4695927; hsa-mir-1185-1/Downstream/1241640;
Nearest TSS
ENST00000550708/Upstream/25695; ENST00000547420/Downstream/12448;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/174862, chr14-CpG: 62/Downstream/97903
Upstream sequence
cggataaagagaaaggagaattgaactttgtcttagctctaccatggccctgtttgacccagaacaagGCCCAAGAATAAAATGTATTACTGCCTCTTCT
Downstream sequence
tgtatgatggtggtccttatggattataaaactcaatttttactgtagattttacatttataatactctattttagctgtagggattataatactttatt
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
Curate