Basic Information
VIS ID
TVIS10018854
Fusion event
HBV-chr4 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1717
Integrated sequence
CACCGTGAACGCCCACCAAATATTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGAC| |TGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCAT
Host Sequence
Chromosome
chr4
Cytoband
p15.1
Reference genome
GRCh37.55
Start
35661100/35659478 (Hg38)
End
35661100/35659478 (Hg38)
Fragile sites / regions
FRA4D
Nearest miRNA
hsa-mir-12113/Upstream/6839810; hsa-mir-1243/Downstream/766888;
Nearest TSS
ENST00000502981/Upstream/990712; ENST00000502245/Downstream/386556;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/4936258, chr4-CpG: 100/Downstream/584531
Nearby gene
ARAP2
Upstream sequence
TGGTAACATCTTGAATGAAAAAGTGACCAATGAAACGACAaaagagagaaagggaaagagagagagatgggcagtggaaaggaaaaaggaaggaagaaaa
Downstream sequence
tggcaggccccggtgtgtcattttAAGTAACATAATATTATGTGACTTAGATACTCTCTCAGTCACAGAGTATAAATTAGTAACGATACCATCTAAAGta
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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