Basic Information
VIS ID
TVIS10018856
Fusion event
HBV-TRMT10A integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1482
Integrated sequence
CTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTTTACGTCCCGTCGGCGCTGAATCCTGCGGACGACCCTTCTCGGGGTCGCTTGGGAC| |TCTCTCGTCCCCTTCTCCGTCTGCCGTTCCGACCGACCACGGGGCGCACCTCTCTTTACGCGGACTCCCCGTCTGTGCCTTCTCATCTGCCGGACCGTGT
Host Sequence
Chromosome
chr4
Cytoband
q23
Reference genome
GRCh37.55
Start
100481069/99559912 (Hg38)
End
100481069/99559912 (Hg38)
Location type
Intron7
Target gene
TRMT10A
miRNAs that regulate target gene
hsa-mir-375
Nearest miRNA
hsa-mir-12113/Upstream/562452; hsa-mir-1243/Downstream/1680883;
Nearest TSS
ENST00000502981/Upstream/2382; ENST00000504724/Downstream/3756;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/470934, chr4-CpG: 40/Downstream/3658
Upstream sequence
AATTTTAGAAGTCTTACATTGTTTATAACATTACCTGAGAGTAATTTTATTCTGTCATACAATATATCAAATTTTTTCTTTGTTtctttctctcgtcctc
Downstream sequence
aatatatacattacgaccaacttttttaaaaaGGTATACACACACACGTTTAATTCTTACCCACAGTTTTCTGCATTTTCTAAAGttatataatgaaaat
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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