Basic Information
VIS ID
TVIS10018864
Fusion event
HBV-TIMM23B integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1810
Integrated sequence
CAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCA| |GCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACAT
Host Sequence
Chromosome
chr10
Cytoband
q11.22
Reference genome
GRCh37.55
Start
51496064/46099756 (Hg38)
End
51496064/46099756 (Hg38)
Location type
Intron7
Fragile sites / regions
FRA10G
Target gene
TIMM23B
Nearest miRNA
hsa-mir-1265/Upstream/935668; hsa-mir-107/Downstream/2885756;
Nearest TSS
ENST00000439456/Upstream/53487; ENST00000610892/Downstream/186589;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/69006, chr10-CpG: 71/Downstream/6421
Upstream sequence
ATTGTTTTGGAGTCAGCCCAGCTATCCAGACTATACCATCTGCACTGTGTCCTGAACTTTCTCAATTTCCCATCTGACTCTTCCCTGTATTTTTAGATTA
Downstream sequence
gtatttaagggctggaAGGACCCTTAGGTATCTTTAGGTCTTCCTAATCTTTTTCATGCCATTGCCTATACAGAAAATGGTATTTCTATAACACAAATAA
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
Curate