HYDIN _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10018865
Fusion event
HBV-HYDIN integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1819
Integrated sequence
TTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGC| |AACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTA
Host Sequence
Chromosome
chr16
Cytoband
q22.2
Reference genome
GRCh37.55
Start
71046083/71012180 (Hg38)
End
71046283/71012380 (Hg38)
Location type
Intron63
Target gene
HYDIN
Nearest miRNA
hsa-mir-1225/Upstream/981758; hsa-mir-11401/Downstream/5856556;
Nearest TSS
ENST00000527434/Upstream/37611; ENST00000568931/Downstream/48206;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/210785, chr16-CpG: 29/Downstream/218077
Upstream sequence
AGAGATtgtattagtccattttcacactgctgataaagacatagctgagcctgggaagaaaaagagatgtttttgtttgtttgtttgagatggtgtctcg
Downstream sequence
CACAAACTCACAGGCTTCAAAGGCAATGGCTGCCTTTTCCTCTTACCGAGGACTTATTTAGCATGCTTGTCCATTTTACTTCTTTCTTTGTTCTTAGATG
Target sequence
GCCATGAAGCATTGTGTTGTTATCAAGCTGATCAGTTAGACTGAAGAGATGGACCTAATAAAAGGGTGGCTCCTGCAGCGACAGCTGTGTGGTCATGAATGGCCAGCCCCGGCACTTCCTGCCAGCTTTCTCATTACATGCAGATGTGGGAGGGGGAGAGACCACCATCCACCATGGTTGACCCAGCTTCCTGTCACGGG
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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