VISDB Viral Integration Site DataBase

VIS ID

TVIS10018871

Fusion event

HBV-NEGR1 integration

Validated

No

Detection method

VirusFinder

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HBV

Reference genome

Start

1724

Integrated sequence

AACGCCCACCAAATATTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGT| |TTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTT

Chromosome

chr1

Cytoband

p31.1

Reference genome

Start

End

72324165/71858482 (Hg38)

Location type

Intron5

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-4769-5p ; hsa-mir-4654 ; hsa-mir-6778-5p ; hsa-mir-1233-5p ; hsa-mir-4648 ; hsa-mir-4437 ; hsa-mir-6739-5p ; hsa-mir-6733-5p ; hsa-mir-3153 ; hsa-mir-4668-5p ; hsa-mir-24-3p ; hsa-mir-3185 ; hsa-mir-299-3p ; hsa-mir-5088-5p ; hsa-mir-4524b-3p ; hsa-mir-561-3p ; hsa-mir-1277-5p ; hsa-mir-4446-5p ; hsa-mir-5006-3p ; hsa-mir-4755-5p ; hsa-mir-183-3p ; hsa-mir-670-5p ; hsa-mir-190a-3p ; hsa-mir-3140-5p ; hsa-mir-4319 ; hsa-mir-125b-5p ; hsa-mir-125a-5p ; hsa-mir-4732-3p ; hsa-mir-345-3p ; hsa-mir-5011-5p ; hsa-mir-4314 ; hsa-mir-7977 ; hsa-mir-920 ; hsa-mir-6726-5p ; hsa-mir-5591-5p ; hsa-mir-4300 ; hsa-mir-6090 ; hsa-mir-6827-5p ; hsa-mir-4284 ; hsa-mir-6506-5p ; hsa-mir-619-5p ; hsa-mir-3192-5p ; hsa-mir-4646-5p ; hsa-mir-204-3p ; hsa-mir-4680-3p ; hsa-mir-576-5p ; hsa-mir-4263 ; hsa-mir-4443 ; hsa-mir-6515-5p ; hsa-mir-421 ; hsa-mir-505-3p ; hsa-mir-7159-5p ; hsa-mir-6792-5p ; hsa-mir-6894-5p ; hsa-mir-765 ; hsa-mir-7154-3p ; hsa-mir-766-5p ; hsa-mir-3145-3p ; hsa-mir-545-3p ; hsa-mir-330-3p ; hsa-mir-5002-5p ; hsa-mir-4272 ; hsa-mir-1179 ; hsa-mir-6838-5p ; hsa-mir-497-5p ; hsa-mir-424-5p ; hsa-mir-195-5p ; hsa-mir-16-5p ; hsa-mir-15b-5p ; hsa-mir-15a-5p ; hsa-mir-513c-3p ; hsa-mir-513a-3p ; hsa-mir-3606-3p ; hsa-mir-4422 ; hsa-mir-629-3p ; hsa-mir-4279 ; hsa-mir-6830-3p ; hsa-mir-4482-5p ; hsa-mir-3130-5p ; hsa-mir-548as-3p ; hsa-mir-548z ; hsa-mir-548h-3p ; hsa-mir-548d-3p ; hsa-mir-548bb-3p ; hsa-mir-548ac ; hsa-mir-4659b-3p ; hsa-mir-4659a-3p ; hsa-mir-6875-3p ; hsa-mir-6809-3p ; hsa-mir-6833-3p ; hsa-mir-4768-5p ; hsa-mir-4753-3p ; hsa-mir-6868-3p ; hsa-mir-1248 ; hsa-mir-1237-3p ; hsa-mir-335-3p ; hsa-mir-6823-3p ; hsa-mir-2114-3p ; hsa-mir-4742-3p ; hsa-mir-4528 ; hsa-mir-6877-3p ; hsa-mir-6819-3p

Nearest miRNA

hsa-mir-101-1/Upstream/790766; hsa-mir-11399/Downstream/5201661;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/777382, chr1-CpG: 55/Downstream/424844

Upstream sequence

tgctgcaggggtggagcccccatggagaacctttgctagggcaatgcagaagggatatgtggggttggagcccccacagaaagtccccactgggacactg

Downstream sequence

cttctaaactactgtccaggtcctacagaaaacagaaagttacccatatgagtaaaaagggagagtgctatttcaacaaaaactaccataaaactcaggg