Basic Information
VIS ID
TVIS10018873
Fusion event
HBV-chr1 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1825
Integrated sequence
TAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTT| |TTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGA
Host Sequence
Chromosome
chr1
Cytoband
q25.1
Reference genome
GRCh37.55
Start
173975753/174006615 (Hg38)
End
173975753/174006615 (Hg38)
Fragile sites / regions
FRA1G
Nearest miRNA
hsa-mir-101-1/Upstream/1861971; hsa-mir-1182/Downstream/1961755;
Nearest TSS
ENST00000473358/Upstream/13543; ENST00000424181/Downstream/15682;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/137836, chr1-CpG: 93/Downstream/15052
Nearby gene
RC3H1
Upstream sequence
TCTACTAGGTTTCTTCCTGCTTACTTCTCAATTCCAGGGACATTCTGGTAGTCTTTGAGCAGCGTAGAGGGAGGTGGGTCATCATCCAGCCTAGACTGGG
Downstream sequence
agccttcagggatcctaactgaaaaacttgaaaggttccactacgcctttttcttgtcatgtcttgaaattttacttttatctccaccgcgttatgagac
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
Curate