Basic Information
VIS ID
TVIS10018877
Fusion event
HBV-chr2 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1804
Integrated sequence
ATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGC| |GCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCAT
Host Sequence
Chromosome
chr2
Cytoband
q22.1
Reference genome
GRCh37.55
Start
139613521/138855951 (Hg38)
End
139613521/138855951 (Hg38)
Fragile sites / regions
FRA2S
Nearest miRNA
hsa-mir-128-1/Upstream/3190473; hsa-mir-10b/Downstream/1730675;
Nearest TSS
ENST00000437798/Upstream/75603; ENST00000429008/Downstream/510214;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/74871, chr2-CpG: 58/Downstream/3274204
Nearby gene
YY1P2
Upstream sequence
CCACACTTAGAAAGCAATCGGTTCTGCCATATTAAAATGAGAGCAGaatattttttaaaaaattaaatataCATCCCTGAGTATCTTGTTCCATtttttt
Downstream sequence
atagatccccatcaatcctcataactatgtgagataatagcaaaatgattattattttaacttcctagattctggtgagatttgttgtacattcataggt
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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