Basic Information
VIS ID
TVIS10018878
Fusion event
HBV-chr2 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1826
Integrated sequence
AAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTT| |TCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAA
Host Sequence
Chromosome
chr2
Cytoband
q32.1
Reference genome
GRCh37.55
Start
187683550/186818823 (Hg38)
End
187683554/186818827 (Hg38)
Nearest miRNA
hsa-mir-10b/Upstream/2439779; hsa-mir-1244-1/Downstream/1478665;
Nearest TSS
ENST00000437798/Upstream/123536; ENST00000453517/Downstream/30343;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/124538, chr2-CpG: 23/Downstream/30292
Nearby gene
ZSWIM2
Upstream sequence
TGGAAATGTGAGATGGCTGTGGTGCATTCCACTGGATGGGGTGGGAGTTGGGCTGACTCGGAGTCTCAGTGATAAATACTTCGACAGGACCACTTGAGCC
Downstream sequence
AAACTTTTCAATTTTCTTTGTCCTTTTGCTCCTTTATACTATAAGAAGAATGCACTAGCATAAAGGTACTATTAGAGCACCCAAGGCTCAAGTTGATCTT
Target sequence
TTCA
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
Curate