Basic Information
VIS ID
TVIS10018879
Fusion event
HBV-chr3 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1236
Integrated sequence
CTGAACCTTTACCCCGTTGCCCGGCAACGGCCAGGTCTGTGCCAAGTGTTTGCTGACGCAACCCCCACTGGCTGGGGCTTGGTCATGGGCCATCAGCGCA| |TGCGTGGAACCTTTTCGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCCGCTTGTTTTGCTCGCAGCAGGTCTGGAGCAAACATTATCGGGACTGA
Host Sequence
Chromosome
chr3
Cytoband
p26.3
Reference genome
GRCh37.55
Start
2066525/2024841 (Hg38)
End
2066532/2024848 (Hg38)
Nearest miRNA
hsa-let-7g/Downstream/3225329;
Nearest TSS
ENST00000440867/Upstream/37371; ENST00000490876/Downstream/73965;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/1715631, chr3-CpG: 182/Downstream/73497
Nearby gene
CNTN4
Upstream sequence
tatggagacctggagggtgagaagccagccatttaaaaagcagagaaaactgtgttcctgggaagggattagcaaggtcacaaaggcactggggtgagga
Downstream sequence
GAATTTGTCATTACGCCTTTCAAGTTATCTCCAAATCCCACCTGCTTTCAGATCCTCAGAAGCTGGCTTTCTGTTTTGCTATGATTGCTCAATAGAAAAT
Target sequence
ATTCTGA
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
Curate