SPINK8 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10018880
Fusion event
HBV-SPINK8 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1704
Integrated sequence
GTCGCATGGAGACCACCGTGAACGCCCACCAAATATTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGC| |ATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGC
Host Sequence
Chromosome
chr3
Cytoband
p21.31
Reference genome
GRCh37.55
Start
48351962/48310472 (Hg38)
End
48351962/48310472 (Hg38)
Location type
Intron2
Target gene
SPINK8
Nearest miRNA
hsa-mir-12127/Upstream/113856; hsa-let-7g/Downstream/5888;
Nearest TSS
ENST00000440867/Upstream/8787; ENST00000436231/Downstream/17869;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/8704, chr3-CpG: 130/Downstream/118349
Upstream sequence
CTTACCCTGGACACTTCCTCATTCCTGGAAAGGAATATAACTATTCATCAGCTATAATGATGAAATCTCATTTTTATATATTGTATTTTTACCTTTAACT
Downstream sequence
tactgaattctaccaaaaaaaaaattttttttttttttttttgagacagagttttgctcttgttgcccaggctggagtgcagtggcacgatctcagctca
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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