Basic Information
VIS ID
TVIS10018884
Fusion event
HBV-chr3 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1782
Integrated sequence
TGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGG| |CTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGT
Host Sequence
Chromosome
chr3
Cytoband
q13.13
Reference genome
GRCh37.55
Start
110940723/111221876 (Hg38)
End
110940723/111221876 (Hg38)
Nearest miRNA
hsa-let-7g/Upstream/1618979; hsa-mir-12124/Downstream/890925;
Nearest TSS
ENST00000440867/Upstream/29525; ENST00000460744/Downstream/70843;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/149322, chr3-CpG: 21/Downstream/452604
Nearby gene
NECTIN3
Upstream sequence
aaaagcaaataaagatgtacttctcttcaggtacgtgcttatttttatttttagaacctcatgcttattgctaacagttatgtttcatcttcatgttcac
Downstream sequence
gactatgtctattttatttatctctagccctagtagcacaatgactagATGGAAAAATAAATTCCCATTCATATCCAACTTGGTGATGCCATCTCTTTTT
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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