Basic Information
VIS ID
TVIS10018889
Fusion event
HBV-chr4 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1821
Integrated sequence
TGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAA| |CTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATA
Host Sequence
Chromosome
chr4
Cytoband
q12
Reference genome
GRCh37.55
Start
58759039/57892873 (Hg38)
End
58759039/57892873 (Hg38)
Fragile sites / regions
FRA4B
Nearest miRNA
hsa-mir-12113/Upstream/5180126; hsa-mir-1243/Downstream/3029746;
Nearest TSS
ENST00000502981/Upstream/172838; ENST00000513836/Downstream/643455;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/696924, chr4-CpG: 222/Downstream/3307292
Nearby gene
LINC02380
Upstream sequence
CATTTCAGCAATTGTGGCACAGAAGTGATGGCTGAAACAAAGAGAATTCCAAGAGACGGAGAATACAGAAAGAAGTGATATATGAATTAACCCTGAGAAA
Downstream sequence
ATTTTGTTTGACATGGATATAAAGGATTGAGATTCTTATATGTCTATTACATTTTGAGTGATCATTTAAAAAGTAGATATAAGTGGTCATGATTTCAAAA
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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