Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10018897
Fusion event
HBV-MCC integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Start
1809
Integrated sequence
TCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACC| |AGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACA
Host Sequence
Chromosome
chr5
Cytoband
q22.2
Reference genome
End
112491698/113156001 (Hg38)
Location type
Intron16
Target gene
miRNAs that regulate target gene
hsa-mir-9-5p ; hsa-mir-26b-5p ; hsa-mir-494-3p ; hsa-mir-527 ; hsa-mir-518a-5p ; hsa-mir-219b-5p ; hsa-mir-3973 ; hsa-mir-5692a ; hsa-mir-559 ; hsa-mir-548y ; hsa-mir-548w ; hsa-mir-548o-5p ; hsa-mir-548j-5p ; hsa-mir-548i ; hsa-mir-548h-5p ; hsa-mir-548d-5p ; hsa-mir-548c-5p ; hsa-mir-548bb-5p ; hsa-mir-548b-5p ; hsa-mir-548ay-5p ; hsa-mir-548au-5p ; hsa-mir-548as-5p ; hsa-mir-548ar-5p ; hsa-mir-548aq-5p ; hsa-mir-548ap-5p ; hsa-mir-548am-5p ; hsa-mir-548ak ; hsa-mir-548ae-5p ; hsa-mir-548ad-5p ; hsa-mir-548ab ; hsa-mir-548a-5p ; hsa-mir-2355-5p ; hsa-mir-1306-5p ; hsa-mir-4687-5p ; hsa-mir-548aw ; hsa-mir-4451 ; hsa-mir-379-5p ; hsa-mir-3529-5p ; hsa-mir-6716-5p ; hsa-mir-4650-3p ; hsa-mir-1468-3p ; hsa-mir-548x-5p ; hsa-mir-548g-5p ; hsa-mir-548f-5p ; hsa-mir-4790-3p ; hsa-mir-548aj-5p ; hsa-mir-519c-3p ; hsa-mir-519b-3p ; hsa-mir-519a-3p ; hsa-mir-548t-5p ; hsa-mir-548az-5p ; hsa-mir-93-5p ; hsa-mir-20b-5p ; hsa-mir-519d-3p ; hsa-mir-526b-3p ; hsa-mir-20a-5p ; hsa-mir-106a-5p ; hsa-mir-106b-5p ; hsa-mir-17-5p ; hsa-mir-301b-3p ; hsa-mir-454-3p ; hsa-mir-4295 ; hsa-mir-130a-3p ; hsa-mir-130b-3p ; hsa-mir-301a-3p ; hsa-mir-3666 ; hsa-mir-19b-3p ; hsa-mir-19a-3p
Nearest miRNA
hsa-mir-10397/Upstream/2642086; hsa-mir-103a-1/Downstream/3099742;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/178692, chr5-CpG: 37/Downstream/138521
Nearest cancer related gene
MCC(TSG, No orient, 0)
Upstream sequence
tttggctatgagagctagaatgtctggttccaactccagttccacaacatgaaagctgcgtgacactgagcaagtcactcaataactctgtctgagtttc
Downstream sequence
tccatccttgctgtttggtatcttatgtgatggatggagctctagcagccatcttgtgctacaaagctgagactctagggagcagaaaggtgcctcagtc
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.