hsa-mir-4434 _LIHC.png
FBXW11 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10018898
Fusion event
HBV-FBXW11 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1797
Integrated sequence
TTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATT| |GGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTT
Host Sequence
Chromosome
chr5
Cytoband
q35.1
Reference genome
GRCh37.55
Start
171365717/171938713 (Hg38)
End
171365717/171938713 (Hg38)
Location type
Intron11
Fragile sites / regions
FRA5G
Target gene
FBXW11
miRNAs that regulate target gene
hsa-mir-148b-3p ; hsa-mir-450a-5p ; hsa-mir-16-5p ; hsa-mir-192-3p ; hsa-mir-6892-5p ; hsa-mir-6878-5p ; hsa-mir-504-3p ; hsa-mir-5703 ; hsa-mir-4516 ; hsa-mir-4434 ; hsa-mir-1909-5p ; hsa-mir-6770-5p ; hsa-mir-6760-5p ; hsa-mir-4475 ; hsa-mir-4433b-3p
Nearest miRNA
hsa-mir-10397/Upstream/551953; hsa-mir-10523/Downstream/723452;
Nearest TSS
ENST00000502646/Upstream/29854; ENST00000398186/Downstream/39043;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/308377, chr5-CpG: 97/Downstream/67287
Upstream sequence
GTTTCTTCCAGGCAAAGGCAGCTCGAGCATCTCATCTGACGTGAGTTCAAGTACAGATCACACGCCCACTAAAGCCCAGAAGAATGTGGCTACCAGCGAA
Downstream sequence
agtcattgtttgtaatttcaaaaaaaatggaaacaacctacatgctcatacgaaagacactggctgaataaactatggcatatgaacacaacagagtact
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
Curate