Basic Information
VIS ID
TVIS10018899
Fusion event
HBV-chr6 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1751
Integrated sequence
TTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGG| |AGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGT
Host Sequence
Chromosome
chr6
Cytoband
p12.3
Reference genome
GRCh37.55
Start
50043463/50075750 (Hg38)
End
50043463/50075750 (Hg38)
Nearest miRNA
hsa-mir-10398/Upstream/4877980; hsa-mir-10524/Downstream/2068599;
Nearest TSS
ENST00000381078/Upstream/27099; ENST00000415106/Downstream/17866;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/524277, chr6-CpG: 57/Downstream/638871
Nearby gene
DEFB112
Upstream sequence
AATTAGTGGGAAAATAGTGTTATCCAAGATTTTAAGAATCTAGTGTGTGTGTTTGTGTGTGTAGGATGGGTTTTTCTGAAATATTTTACTTGCATGTGAA
Downstream sequence
TTTTGTTTTAATGTGATGTTTTGGATTATAGAGTCATTTTATCTTCTTTTAAAGTTTCTATTTTGCAGGAAGTAATTAATTGAATGTATTGACTTTGAAC
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
Curate