Basic Information
VIS ID
TVIS10018904
Fusion event
HBV-chr8 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1793
Integrated sequence
GACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATA| |AATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGG
Host Sequence
Chromosome
chr8
Cytoband
q12.1
Reference genome
GRCh37.55
Start
57727433/56814874 (Hg38)
End
57727437/56814878 (Hg38)
Nearest miRNA
hsa-mir-124-1/Upstream/13918599; hsa-mir-10400/Downstream/4899910;
Nearest TSS
ENST00000518652/Upstream/158409; ENST00000519314/Downstream/165234;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/366618, chr8-CpG: 77/Downstream/178263
Nearby gene
IMPAD1
Upstream sequence
CTAATACGTCAGATACTGATGGGCATTTTGTAAACTAAGATGATAAACCCCAACGAATTCACACTGTGCTTCTTTATGTGATCATCACATTCTAACTCAA
Downstream sequence
gttttaataaatttaaaaggattcaagttatataaagtatgtgctttgaccataatggaattaagctagaaatcagtaacagaaagatctctggaaaatt
Target sequence
aaat
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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