Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10018908
Fusion event
HBV-HNRNPK integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Start
1805
Integrated sequence
TACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCG| |CACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATG
Host Sequence
Chromosome
chr9
Cytoband
q21.32
Reference genome
Start
End
86583239/83968324 (Hg38)
Location type
Exon1
Target gene
miRNAs that regulate target gene
hsa-mir-450a-5p ; hsa-mir-21-5p ; hsa-mir-877-3p ; hsa-mir-106b-3p ; hsa-mir-615-3p ; hsa-mir-503-5p ; hsa-mir-484 ; hsa-mir-328-3p ; hsa-mir-125b-5p ; hsa-mir-23b-3p ; hsa-mir-15b-5p ; hsa-mir-30c-5p ; hsa-mir-1260b ; hsa-mir-1229-3p ; hsa-mir-6511a-3p ; hsa-mir-6511b-3p ; hsa-mir-6784-3p ; hsa-mir-6862-3p ; hsa-mir-500b-3p ; hsa-mir-590-3p ; hsa-mir-5571-5p ; hsa-mir-649
Nearest miRNA
hsa-mir-101-2/Upstream/13158240; hsa-let-7a-1/Downstream/1424;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/11212, chr9-CpG: 177/Downstream/11087
Upstream sequence
aggccccgcctgcccttccccgagccccctgccccacggtccgtggccccggcccagcgtccgccccgcccggcccggccGCTCCTCAGTCAGCAAAGCA
Downstream sequence
AGGGGATTGGGGACAGAGATGAGAGTGTTTCTCATGGCTGGACAAAAGCAATCAAGTCAACGACAGAGCTGTACTTTCCCATTCCCATGACCTATGAAAT
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.