Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10018913
Fusion event
HBV-CTNNA3 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2017
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Start
1807
Integrated sequence
CTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCA| |CCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGA
Host Sequence
Chromosome
chr10
Cytoband
q21.3
Reference genome
Start
End
69240956/67481198 (Hg38)
Location type
Intron13
Fragile sites / regions
Target gene
miRNAs that regulate target gene
hsa-mir-182-5p ; hsa-mir-5704 ; hsa-mir-4470 ; hsa-mir-3065-5p ; hsa-mir-3613-3p ; hsa-mir-1295b-3p ; hsa-mir-15a-3p ; hsa-mir-4717-5p ; hsa-mir-6826-3p ; hsa-mir-6891-3p ; hsa-mir-6072 ; hsa-mir-6795-3p ; hsa-mir-6887-3p ; hsa-mir-548ay-3p ; hsa-mir-548at-3p ; hsa-mir-548as-3p ; hsa-mir-548t-3p ; hsa-mir-548ap-3p ; hsa-mir-548aa ; hsa-mir-548x-3p ; hsa-mir-548j-3p ; hsa-mir-548aq-3p ; hsa-mir-548am-3p ; hsa-mir-548aj-3p ; hsa-mir-548ah-3p ; hsa-mir-548ae-3p
Nearest miRNA
hsa-mir-1265/Upstream/77785; hsa-mir-107/Downstream/4309549;
Nearest CpG islands
Nearest cancer related gene
CTNNA3(TSG, No orient, 0)
Upstream sequence
AAGTGAATAAATTTTGCTATTACTGTGAAAGTTGCTTTTGTGGAAAAGAAGATTGAATTAAGATGTATGGTAggctgggtgtggtggctcacgcatgtaa
Downstream sequence
tcccctggagagctgaaacaagacaaagatgcccactctcactactcatcttcagcatagtactggaagttctagctgcaacaatgaggcaagagaaaga
Target sequence
cac
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.