Basic Information
VIS ID
TVIS10018915
Fusion event
HBV-BMS1P21 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1791
Integrated sequence
CCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCA| |TAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGT
Host Sequence
Chromosome
chr10
Cytoband
q22.3
Reference genome
GRCh37.55
Start
81675787/79916031 (Hg38)
End
81675787/79916031 (Hg38)
Location type
Intron3
Fragile sites / regions
FRA10D
Target gene
BMS1P21
Nearest miRNA
hsa-mir-1265/Upstream/4363478; hsa-mir-107/Downstream/6348663;
Nearest TSS
ENST00000439456/Upstream/74673; ENST00000608229/Downstream/33072;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/10711, chr10-CpG: 110/Downstream/65441
Upstream sequence
caggttagttacatatgtatacatgtgacatgctggtgtgctgcacccactaactcgtcatctagcattaggtatatctcccagtgctatccctcctccc
Downstream sequence
TCAACTCTTTCCTTTGACTCATCTCCCAATGTACACATGATCATCATCATTCTAATGAAAGGGAAAGAGTGTGTGGATCATCCAAAGGGGTGAGTTGTCC
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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