STK33 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10018917
Fusion event
HBV-STK33 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1821
Integrated sequence
TGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAA| |CTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATA
Host Sequence
Chromosome
chr11
Cytoband
p15.4
Reference genome
GRCh37.55
Start
8501589/8480042 (Hg38)
End
8501589/8480042 (Hg38)
Location type
Intron12
Target gene
STK33
miRNAs that regulate target gene
hsa-mir-183-5p ; hsa-mir-103a-3p ; hsa-mir-16-5p ; hsa-mir-877-3p ; hsa-mir-10b-5p
Nearest miRNA
hsa-mir-210/Upstream/1245205; hsa-let-7a-2/Downstream/610270;
Nearest TSS
ENST00000527297/Upstream/2759; ENST00000534169/Downstream/85869;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/211267, chr11-CpG: 55/Downstream/113808
Upstream sequence
gcctgtgtgtttttctccagagcacttatgcccacccaacatggtccatctcatggttacttactgtttatttggtttattgttcatctccctgaactac
Downstream sequence
aagagagggagaagggggaggccagactctttgaaacacaccagatctcacgtgaactgagagaggactcacttattatcgaggagatgctgctaaacca
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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