Basic Information
VIS ID
TVIS10018918
Fusion event
HBV-chr11 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1825
Integrated sequence
TAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTT| |TTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGA
Host Sequence
Chromosome
chr11
Cytoband
p14.3
Reference genome
GRCh37.55
Start
22416361/22394815 (Hg38)
End
22416361/22394815 (Hg38)
Nearest miRNA
hsa-mir-210/Upstream/2634732; hsa-let-7a-2/Downstream/1024290;
Nearest TSS
ENST00000527297/Upstream/32521; ENST00000531858/Downstream/52561;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/52984, chr11-CpG: 20/Downstream/37939
Nearby gene
LINC01495
Upstream sequence
CCCCCAAATTGTGGCGGTGATTCTCTCccacacaacggccctgcagaggaggctcgcgagcctcgtcggcacagttttccttttacagatggagaaacca
Downstream sequence
AATGCAAAAGATAGGAATGATATAGACAGAGAAAACCAAGATGCATCAATAATTAGTCCCCCATCAGCCTTGGGGGCAGCCTGGTGCTGCTCATCATCTG
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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