Basic Information
VIS ID
TVIS10018920
Fusion event
HBV-ZBTB44-DT integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1922
Integrated sequence
TTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAA| |AGAATTTGGAGCTACTGTGGAGTTACTCTCGTTTTTGCCTTCTGACTTCTTTCCTTCAGTACGAGATCTTCTAGATACCGCCTCAGCTCTGTATCGGGAA
Host Sequence
Chromosome
chr11
Cytoband
q24.3
Reference genome
GRCh37.55
Start
130192769/130322874 (Hg38)
End
130192919/130323024 (Hg38)
Location type
Intronic
Target gene
ZBTB44-DT
Nearest miRNA
hsa-let-7a-2/Upstream/1800425; hsa-mir-4697/Downstream/343711;
Nearest TSS
ENST00000527297/Upstream/7835; ENST00000616197/Downstream/78878;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/8117, chr11-CpG: 121/Downstream/104482
Nearby gene
ADAMTS8
Upstream sequence
gcaaggcgggcagtgtagctggagctgagtgcacaaggcagaaagcagtgggatgtgagatggagaaaagaatgtgggaggccactcacttggaaccttg
Downstream sequence
aggctgacattctgtctctcagtaagtccaacctagaggattttccttgcagcattggaacagatggctcatccttctattgagccccagaggaagtcat
Target sequence
TTGTTTTCTGCTCTATTAGTAAAACTGAAAATTCTCTAAAAATTTAAAATGTGCATTACAAATTgaagatcatgtatagtcaacattactgttgaagatctcttaaattgcccataaggcacaatatattgcatttatgagccaccttgg
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
Curate