PIBF1 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10018926
Fusion event
HBV-PIBF1 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1769
Integrated sequence
GGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCT| |TTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAA
Host Sequence
Chromosome
chr13
Cytoband
q22.1
Reference genome
GRCh37.55
Start
73391661/72817523 (Hg38)
End
73391661/72817523 (Hg38)
Location type
Intron5
Fragile sites / regions
FRA13B
Target gene
PIBF1
Nearest miRNA
hsa-mir-1297/Upstream/6599199; hsa-mir-1267/Downstream/4880489;
Nearest TSS
ENST00000623511/Upstream/19614; ENST00000486330/Downstream/66921;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/35049, chr13-CpG: 163/Downstream/241199
Upstream sequence
ATCTACTTCTTTTAAAACCTACTTAAGAATCACTTTGTTTAAATGTGTTCTTTGAATTAATACTGGGGTCTTGCCTTCCTATTCATAGTTATATTTCCCA
Downstream sequence
TTTCAATTCACATACTTGTTATCTATTTGCTCTCTGATTTTAAACTTGCTGAGCCTTTGGATTACTTACGATACTTCTATGTTAAAGCTTTAAGCTATCT
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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