Basic Information
VIS ID
TVIS10018930
Fusion event
HBV-chr16 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1724
Integrated sequence
AACGCCCACCAAATATTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGT| |TTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTT
Host Sequence
Chromosome
chr16
Cytoband
q12.1
Reference genome
GRCh37.55
Start
52297741/52263829 (Hg38)
End
52297749/52263837 (Hg38)
Location type
Intronic
Target gene
CASC22 ; LOC105371261
Nearest miRNA
hsa-mir-1225/Upstream/1521452; hsa-mir-11401/Downstream/3981683;
Nearest TSS
ENST00000527434/Upstream/5265; ENST00000628396/Downstream/7735;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/1107480, chr16-CpG: 125/Downstream/281887
Nearby gene
TOX3
Upstream sequence
TACCCATGTGGTATAATAATGAGCTTGCACTTTGGTATTTTCTGGTTTAACCTTCAGAAAGTTTTGTCAGTCACTCATGGGAACAAGGTATAATATACAA
Downstream sequence
CAATGAAGGTTGAGGGTTGACTCTGAAGGCCAAGATGCAAACCTGGCAAGCAGAAGGCTTGTGGTTTTGATAAATCCCGAGCCATTGTTTGATAGGAAAA
Target sequence
GTGTATTT
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
Curate