Basic Information
VIS ID
TVIS10018938
Fusion event
HBV-LOC100420587 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1786
Integrated sequence
AACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGT| |AGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCT
Host Sequence
Chromosome
chr19
Cytoband
q12
Reference genome
GRCh37.55
Start
29096979/28606072 (Hg38)
End
29096979/28606072 (Hg38)
Location type
Intron5
Target gene
LOC100420587
Nearest miRNA
hsa-mir-10395/Upstream/8206718; hsa-let-7e/Downstream/6516628;
Nearest TSS
ENST00000633603/Upstream/70795; ENST00000587961/Downstream/616;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/696147, chr19-CpG: 67/Downstream/121022
Upstream sequence
TGCTTCAGTAGGCTAATTGAGTATCTAAACAAACTAATTAATCACAGGAATTCATACAAGATGGACAGGTCTGGAGAGGTGATGTTCATCAAACCCCTCC
Downstream sequence
GCAGGTTAAAATTAGAATGGGAACCGTGCAGCGCATTGGGTGGTAGAAAATAGTTGACAACTCTCTCAGAGTTTATTCATTCCAACAATAGAACCCGCTG
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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