VISDB Viral Integration Site DataBase

VIS ID

TVIS10018940

Fusion event

HBV-RBFOX2 integration

Validated

No

Detection method

VirusFinder

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HBV

Reference genome

Start

1797

Integrated sequence

TTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATT| |GGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTT

Chromosome

chr22

Cytoband

q12.3

Reference genome

Start

End

36255690/35859643 (Hg38)

Location type

Intron12

Target gene

miRNAs that regulate target gene

hsa-mir-320d ; hsa-mir-498 ; hsa-mir-9-5p ; hsa-mir-32-5p ; hsa-mir-30a-5p ; hsa-let-7b-5p ; hsa-mir-186-5p ; hsa-let-7a-5p ; hsa-mir-3923 ; hsa-mir-432-3p ; hsa-mir-432-5p ; hsa-mir-106a-3p ; hsa-mir-203b-3p ; hsa-mir-7154-5p ; hsa-mir-4755-3p ; hsa-mir-628-3p ; hsa-mir-8060 ; hsa-mir-4650-5p ; hsa-mir-575 ; hsa-mir-4676-5p ; hsa-mir-6858-3p ; hsa-mir-25-3p ; hsa-mir-92a-3p ; hsa-mir-92b-3p ; hsa-mir-363-3p ; hsa-mir-367-3p ; hsa-mir-921 ; hsa-mir-1294 ; hsa-mir-630 ; hsa-mir-202-3p ; hsa-mir-3163 ; hsa-mir-3174 ; hsa-mir-548l ; hsa-mir-3133 ; hsa-mir-548n ; hsa-let-7e-5p ; hsa-let-7d-5p ; hsa-let-7c-5p ; hsa-let-7f-5p ; hsa-let-7g-5p ; hsa-let-7i-5p ; hsa-mir-4458 ; hsa-mir-4500 ; hsa-mir-98-5p ; hsa-mir-4272 ; hsa-mir-6074 ; hsa-mir-7109-5p ; hsa-mir-6881-3p ; hsa-mir-6780a-3p ; hsa-mir-7111-3p ; hsa-mir-4326 ; hsa-mir-6885-5p ; hsa-mir-328-5p ; hsa-mir-6887-5p ; hsa-mir-6795-5p ; hsa-mir-637 ; hsa-mir-4729 ; hsa-mir-136-5p ; hsa-mir-548e-5p ; hsa-mir-1253 ; hsa-mir-3928-5p ; hsa-mir-449b-3p ; hsa-mir-6770-5p ; hsa-mir-6806-3p ; hsa-mir-6854-5p ; hsa-mir-1910-3p ; hsa-mir-3148 ; hsa-mir-3714 ; hsa-mir-4484 ; hsa-mir-548an ; hsa-mir-6511a-5p ; hsa-mir-651-3p ; hsa-mir-6768-3p

Nearest miRNA

hsa-mir-1286/Upstream/522844; hsa-let-7a-3/Downstream/427204;

Nearest TSS

Nearest CpG islands

None/Target, chr22-CpG: 279/Upstream/307694, chr22-CpG: 131/Downstream/168528

Upstream sequence

CCTTTGCATGACACATGGTACAGAAAGGAAGTATGGGTAATAACAGAGTAAACCATGGAATGGCTGATATGCATTTCTGTTTTGGAATGAGAGACATGGC

Downstream sequence

ATACAAACTGTGAGGCAAGGAATTAGCAGTTTTGTTAAAAGTGTCATTCATAAATCAGTAAATGGATAGGACAATAGTTATTCACtttttgtttttaagt