Basic Information
VIS ID
TVIS10018942
Fusion event
HBV-chrX integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1817
Integrated sequence
TGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCAT| |GCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCT
Host Sequence
Chromosome
chrX
Cytoband
q21.31
Reference genome
GRCh37.55
Start
87094717/87839717 (Hg38)
End
87094717/87839717 (Hg38)
Nearest miRNA
hsa-let-7f-2/Upstream/1936010; hsa-mir-105-1/Downstream/7223424;
Nearest TSS
ENST00000429181/Upstream/88834; ENST00000373111/Downstream/907508;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/1690844, chrX-CpG: 43/Downstream/3594886
Nearby gene
KLHL4
Upstream sequence
ATGAAACTCATGGGGTCTGTTGGGGAGACTCATGTGGCTTGTCTTAGGTCCTGACTAGATATGGCTTGCTGCCACTTACTCTTTATGGACACTACACTAT
Downstream sequence
ggaatgtgatctgcaaaatctgtgctgtaggatattacagaaaaaataatccagtatcttcagttacacagaggaaaaagagaaggaaatagaagcctat
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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