Basic Information
VIS ID
TVIS10018943
Fusion event
HBV-XACT integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1822
Integrated sequence
GTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAAC| |TTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAA
Host Sequence
Chromosome
chrX
Cytoband
q23
Reference genome
GRCh37.55
Start
113110598/113867315 (Hg38)
End
113110598/113867315 (Hg38)
Location type
Intron2
Target gene
XACT
Nearest miRNA
hsa-let-7f-2/Upstream/1086527; hsa-mir-105-1/Downstream/772120;
Nearest TSS
ENST00000429181/Upstream/1026500; ENST00000371951/Downstream/70903;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/1025728, chrX-CpG: 18/Downstream/523182
Upstream sequence
aggccccctgccttccctacacatcaagctcgaggatttgccccacccaggactggcaaattagctttactcaacaagccctgagtcagataactaaaat
Downstream sequence
ACTTCTGAAGATTCTACATGAGTGAGAGAAAGAGAGACAGAAAgtgagtgtgtgtgtgtgtgtgtgtgtctgttgtgtgtgtgttgtgtgtgtAGCCTGC
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
Curate