Basic Information
VIS ID
TVIS10018946
Fusion event
HBV-chr1 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Host Sequence
Chromosome
chr1
Cytoband
p22.1
Reference genome
GRCh37.55
Start
93263261/92797704 (Hg38)
End
93263261/92797704 (Hg38)
Fragile sites / regions
FRA1D
Nearest miRNA
hsa-mir-101-1/Upstream/6440017; hsa-mir-11399/Downstream/1049128;
Nearest TSS
ENST00000473358/Upstream/5300; ENST00000646852/Downstream/34279;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/12165, chr1-CpG: 55/Downstream/34237
Nearby gene
RPL5
Nearest cancer related gene
RPL5(TSG, No orient)
Upstream sequence
CACTGTATGCCCAAGAAAGAAAAAAAAAATCTACAGATGATTAATGCAGTTTTCCATCCTTTTTAACTTTTTCCAGTTCAGCCTTTTCTCTTTTCTTTCA
Downstream sequence
TCCAAATAGGAGCAAAAAATTCTATACCTTTAAAATATATTTTATGTAATCTTTCCACATCAGCATGTGAAGCTCTACTTCATCctgcataatagtctgt
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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