Basic Information
VIS ID
TVIS10018956
Fusion event
HBV-chr2 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Host Sequence
Chromosome
chr2
Cytoband
q14.2
Reference genome
GRCh37.55
Start
120187153/119429577 (Hg38)
End
120187158/119429582 (Hg38)
Fragile sites / regions
FRA2S
Nearest miRNA
hsa-mir-1285-2/Upstream/5708209; hsa-mir-10b/Downstream/7993955;
Nearest TSS
ENST00000437798/Upstream/59360; ENST00000417645/Downstream/319;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/61866, chr2-CpG: 79/Downstream/1864
Nearby gene
TMEM37
Upstream sequence
CTCCAAAAATTTGTCATGttattttgtattttttaaaaattgatattattaaaCAATGATAAGTCAGAGTTTTTAACTGGAGATTATATGTCATCCGGTA
Downstream sequence
CCAGGATTTGAGAGGGCTGTGGATGCTGCCACTCCCCGCACCACCCCAACCCCCTAAGCCAGAGAGGTACCAGGAGACTCCAGGTCTTAGAGTCTCAGCT
Target sequence
TCTCA
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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