MANBA _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10018965
Fusion event
HBV-MANBA integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Host Sequence
Chromosome
chr4
Cytoband
q24
Reference genome
GRCh37.55
Start
103670586/102749429 (Hg38)
End
103670586/102749429 (Hg38)
Location type
Intron16
Target gene
MANBA
miRNAs that regulate target gene
hsa-mir-335-5p
Nearest miRNA
hsa-mir-12113/Upstream/1419015; hsa-mir-1243/Downstream/6739269;
Nearest TSS
ENST00000502981/Upstream/20823; ENST00000501133/Downstream/11504;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/247357, chr4-CpG: 54/Downstream/11250
Upstream sequence
AGAAGTGAAATGAAGCCAGTTGGCTCTGTGAATCCATAAAATATTTATCAAGCCTTGGAGAAAGAGAATTCATCAAAAATTATATTAAAGTGACTAATTT
Downstream sequence
ATGTTTACATTTTTTGAGAGCTTTTAGCAAATGGGGTGCTTTTAGTGGCATATTTTGAACAAAAGTATATTGTACTCATGTCTCTATTTTCATCAGACAC
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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