PPP2R2B _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10018969
Fusion event
HBV-PPP2R2B integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Host Sequence
Chromosome
chr5
Cytoband
q32
Reference genome
GRCh37.55
Start
145980899/146601336 (Hg38)
End
145980988/146601425 (Hg38)
Location type
Intron3
Target gene
PPP2R2B
miRNAs that regulate target gene
hsa-mir-30e-3p ; hsa-mir-6825-5p ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-765 ; hsa-mir-6804-5p ; hsa-mir-665 ; hsa-mir-4779 ; hsa-mir-4459 ; hsa-mir-548t-3p ; hsa-mir-548ap-3p ; hsa-mir-548aa
Nearest miRNA
hsa-mir-10397/Upstream/2921365; hsa-mir-103a-1/Downstream/2460888;
Nearest TSS
ENST00000502646/Upstream/960; ENST00000503975/Downstream/277156;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/153469, chr5-CpG: 97/Downstream/276358
Upstream sequence
ctgacctcaactgatccacctgccttggcctcccaaagtggtgagattacagccatgagccaccacacTATGtttttttgtttttgtttttttgattcaa
Downstream sequence
attgctataaaaagttagccaggcatggtggggcatgcctgtggtcccagctacttgggtggatgagctactattgggccactgcaccccagcctgggca
Target sequence
gcctgtattcagcactttgggaggcctaggcgggaagatcacttaaacccaagatttcaagaccagcctggataacataggaagattct
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
Curate