VISDB Viral Integration Site DataBase

VIS ID

TVIS10018971

Fusion event

HBV-HLA-B integration

Validated

No

Detection method

VirusFinder

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Good

Reported year

2017

PubMed ID

Virus name

HBV

Reference genome

Chromosome

chr6

Cytoband

p21.33

Reference genome

Start

End

31324463/31356686 (Hg38)

Location type

Exon6

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-615-3p ; hsa-mir-3653-3p ; hsa-mir-30e-3p ; hsa-mir-30d-3p ; hsa-mir-30a-3p ; hsa-mir-5047 ; hsa-mir-1301-3p ; hsa-mir-7156-3p ; hsa-mir-222-5p ; hsa-mir-4660 ; hsa-mir-548ax ; hsa-mir-548ao-5p ; hsa-mir-3129-5p ; hsa-mir-199b-3p ; hsa-mir-199a-3p ; hsa-mir-936 ; hsa-mir-10b-3p ; hsa-mir-9500 ; hsa-mir-6822-5p ; hsa-mir-5584-5p ; hsa-mir-6750-5p ; hsa-mir-495-5p ; hsa-mir-6818-3p ; hsa-mir-3620-5p ; hsa-mir-1587 ; hsa-mir-4417 ; hsa-mir-593-3p ; hsa-mir-6895-3p ; hsa-mir-654-5p ; hsa-mir-541-3p ; hsa-mir-6766-5p ; hsa-mir-6756-5p ; hsa-mir-4741 ; hsa-mir-4675 ; hsa-mir-762 ; hsa-mir-5001-5p ; hsa-mir-4498 ; hsa-mir-4492 ; hsa-mir-6829-5p ; hsa-mir-4656 ; hsa-mir-6876-3p ; hsa-mir-626 ; hsa-mir-6845-3p ; hsa-mir-1306-5p

Nearest miRNA

hsa-mir-3143/Upstream/850; hsa-mir-10398/Downstream/277101;

Nearest TSS

Nearest CpG islands

chr6-CpG: 118/Target, None/Upstream, None/Downstream

Upstream sequence

ATTATGAAATGTTTAAAGAAAAATTAAGTGACTAGGATGAGAAAAGATAATATTTAACATATACACATGAAATAATAAACAACATGTACTGGATGAGAGT

Downstream sequence

CCGGCCTCGCTCTGGTTGTAGTAGCCGCGCAGGTTCCGCAGGCTCTCTCGGTCAGTCTGTGCCTGGGCCTTGTAGATCTGTGTGTTCCGGTCCCAATACT

Target sequence

CAGCGCGCTCCAGCTTGTCCTTCCCGTTCTCCAGGTATCTGCGGAGCCACTCCACGCACTCGCCCTCCAGGTAGGCTCTCCGCTGCTCCGCCTCACGGGCCGCCTCCCACTTGCGCTGGGTGATCTGAGCCGCCGTGTCCGCGGCGGTCCAGGAGCGCAGGTCCTCGTTCAGGGCGATGTAATCCTTGCCGTCGTAGGCGTACTGGTCATGCCCGCGGAGGAGGCGCCCGTCCGGCCCCACGTCGCAGCCGTACA