PLG _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10018975
Fusion event
HBV-PLG integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Host Sequence
Chromosome
chr6
Cytoband
q26
Reference genome
GRCh37.55
Start
161143436/160722404 (Hg38)
End
161143598/160722566 (Hg38)
Location type
Intron9
Target gene
PLG
Nearest miRNA
hsa-mir-10398/Upstream/1957651; hsa-mir-1913/Downstream/5786788;
Nearest TSS
ENST00000381078/Upstream/16029; ENST00000493435/Downstream/8174;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/42980, chr6-CpG: 51/Downstream/44486
Upstream sequence
GTGGGGAGTGTGACATCTCAAGAGGGGAAGGCACAGCTATCCAGGAGCTGAAGTGGGGCGGGGGTAGTCTTTTTCAGAGTCTGATTATTGGGTCTGGGTT
Downstream sequence
CGTATGTCTTTGATTTTTACTGTAAGAGGGGCATCAGCCAACTGAAATTTCTGTTAAAAGAGCCATGCTTCATGCTTCAAGCCAACTTCCTAGGACCAAA
Target sequence
CAGCACCACCTGAGCTAACCCCTGTGGTCCAGGACTGCTACCATGGTGATGGACAGAGCTACCGAGGCACATCCTCCACCACCACCACAGGAAAGAAGTGTCAGTCTTGGTCATCTATGACACCACACCGGCACCAGAAGACCCCAGAAAACTACCCAAATG
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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