VISDB Viral Integration Site DataBase

VIS ID

TVIS10018983

Fusion event

HBV-DEPTOR integration

Validated

No

Detection method

VirusFinder

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Good

Reported year

2017

PubMed ID

Virus name

HBV

Reference genome

Chromosome

chr8

Cytoband

q24.12

Reference genome

Start

End

120961628/119949388 (Hg38)

Location type

Intron1

Fragile sites / regions

FRA8C ; FRA8E

Target gene

miRNAs that regulate target gene

hsa-mir-190a-3p ; hsa-mir-4796-5p ; hsa-mir-654-3p ; hsa-mir-5011-5p ; hsa-mir-1277-5p ; hsa-mir-4803 ; hsa-mir-384 ; hsa-mir-3685 ; hsa-mir-3064-3p ; hsa-mir-329-5p ; hsa-mir-624-3p ; hsa-mir-365b-3p ; hsa-mir-365a-3p ; hsa-mir-3191-5p ; hsa-mir-668-3p ; hsa-mir-215-3p ; hsa-mir-6773-3p ; hsa-mir-4653-5p ; hsa-mir-3921 ; hsa-mir-301b-5p ; hsa-mir-301a-5p ; hsa-mir-146a-3p ; hsa-mir-519d-5p ; hsa-mir-26a-2-3p ; hsa-mir-26a-1-3p ; hsa-mir-483-3p ; hsa-mir-8063 ; hsa-mir-3145-5p ; hsa-mir-4668-3p ; hsa-mir-4457 ; hsa-mir-375

Nearest miRNA

hsa-mir-12123/Upstream/623740; hsa-mir-10400/Downstream/3266400;

Nearest TSS

Nearest CpG islands

None/Target, chr8-CpG: 109/Upstream/74635, chr8-CpG: 26/Downstream/174237

Upstream sequence

CATGACCACAATATAACCAGCCTACAACTGGGTCTGCTTAGAATTCAAATATATTTACACATTATTTTTGAGGTTAAACCTCTTTAATGAGTCATTTTGT

Downstream sequence

agaagtagaatggcgggatcatacagtaactctgtgttcaacgatttgaagaactgtgagactattttctgaagtgcctgcaccatttcaaattcccacc

Target sequence

aaactcctgacctcaggtgatccacccgccttggcctcccaaagtgctgggattacaggcatgagccaccatgcccgaccacatttctgtattttgataattttatatcaatggaataatacaatgtatggccttttgtgactgtcttctttcacttggtataatattttcaagatttctccatgttgtagcttgtttcagtacttcacttctgtttatagccaactaattccttgtatgcatacaccacatttt