Basic Information
VIS ID
TVIS10018988
Fusion event
HBV-FRA10AC1 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Host Sequence
Chromosome
chr10
Cytoband
q23.33
Reference genome
GRCh37.55
Start
95445980/93686223 (Hg38)
End
95445980/93686223 (Hg38)
Location type
Intron6
Fragile sites / regions
FRA10D
Target gene
FRA10AC1
miRNAs that regulate target gene
hsa-mir-128-3p ; hsa-mir-181a-5p
Nearest miRNA
hsa-mir-107/Upstream/4093396; hsa-mir-1287/Downstream/2378092;
Nearest TSS
ENST00000439456/Upstream/760; ENST00000478763/Downstream/1718;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/84593, chr10-CpG: 33/Downstream/16180
Upstream sequence
ggtgcaaggtaggaagagactcaaagacacactctaagactcctctgagaggaggccttcagctaaatcatccaagagggatctggtgactgcgggaatg
Downstream sequence
tcccagcactttgggaggccggggtggggggatcgcttgagcccaggggttcaagaccagcctgggaaacatagggaaaccccatctctaccaaaaaaaa
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
Curate