Basic Information
VIS ID
TVIS10018997
Fusion event
HBV-LINC00375 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Host Sequence
Chromosome
chr13
Cytoband
q31.1
Reference genome
GRCh37.55
Start
85678483/85104348 (Hg38)
End
85678684/85104549 (Hg38)
Location type
Intron5
Target gene
LINC00375
Nearest miRNA
hsa-mir-1297/Upstream/7406232; hsa-mir-1267/Downstream/2514116;
Nearest TSS
ENST00000623511/Upstream/25428; ENST00000424926/Downstream/259052;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/1224586, chr13-CpG: 121/Downstream/2566765
Upstream sequence
TTCTTATTTACTCAGTCCTCCAACCCCAAAACTGCTTGCTACTTGTTTTTACCAACCCATGCCCCACTGTTCCCCACTTTCCTAAATCTTTCTTCTGCGT
Downstream sequence
taaaaacattatgctaagtgaagtaagtagaacacaaaaagataaatactgtacaattccacatatatgagatatctaaagtagtcaaatatatagagac
Target sequence
ttttgaaagcatggtctcaaagtatatttgcacacccatattaatgataacactagtaacaatagccaagtgatagaagtaactcaaatgttgattagcagatgactggataaacaaaatgtggtatatgcatgtaacagaatattatcaagccttagaaacaaaggaaatcttgtgagatgctacaacatggatgaacct
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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