Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10019000
Fusion event
HBV-MT1E integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2017
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Host Sequence
Chromosome
chr16
Cytoband
q13
Reference genome
Start
End
56659792/56625880 (Hg38)
Location type
Exon1
Target gene
miRNAs that regulate target gene
hsa-mir-503-5p ; hsa-mir-24-3p ; hsa-mir-4302 ; hsa-mir-3613-5p ; hsa-mir-6733-3p ; hsa-mir-4284 ; hsa-mir-107 ; hsa-mir-103a-3p ; hsa-mir-4668-3p ; hsa-mir-545-3p ; hsa-mir-548c-3p ; hsa-mir-138-2-3p ; hsa-mir-143-5p ; hsa-mir-3665 ; hsa-mir-3944-5p ; hsa-mir-4273 ; hsa-mir-4482-3p ; hsa-mir-4677-5p ; hsa-mir-657 ; hsa-mir-6739-3p ; hsa-mir-7156-5p
Nearest miRNA
hsa-mir-1225/Upstream/380171; hsa-mir-11401/Downstream/232638;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/46, chr16-CpG: 68/Downstream/6153
Upstream sequence
TCTGTTTTACTGCTTAGGGAAAGCCAGCTTTTCTACCCACACACGTTTAGTTTGAAGAGTATCTATTTTTGGAGGGTTCTTTGGGAGGTTGGGCAGGCTT
Downstream sequence
TAAGGGAAGCTCTGCGCCCTGGAATCCCCATTTCCCAGCCCTATTACAGAGGGTCTCTGGGTTTCAGGAAGTCGCATTTTAAGTTCTGAGCGACGGGGAC
Target sequence
CTGCCTGACTGCTTGTTCGTCTCACTGGTGTGAGCTCCAGCATCCCCTTTGCTCGAAATGGACCCCAACTGCTCTTGCGCCACTGG
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.