TSHZ1 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10019006
Fusion event
HBV-TSHZ1 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Host Sequence
Chromosome
chr18
Cytoband
q22.3
Reference genome
GRCh37.55
Start
72959597/75247642 (Hg38)
End
72959597/75247642 (Hg38)
Location type
Intron1
Target gene
TSHZ1
miRNAs that regulate target gene
hsa-mir-1305 ; hsa-mir-498 ; hsa-mir-488-3p ; hsa-mir-4465 ; hsa-mir-26b-5p ; hsa-mir-26a-5p ; hsa-mir-1297 ; hsa-mir-6730-5p ; hsa-mir-5681a ; hsa-mir-6513-3p ; hsa-mir-5582-5p ; hsa-mir-5680 ; hsa-mir-548an ; hsa-mir-124-3p
Nearest miRNA
hsa-mir-1-2/Upstream/2394260;
Nearest TSS
ENST00000575820/Upstream/3066; ENST00000584217/Downstream/35222;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/35415, chr18-CpG: 28/Downstream/40053
Upstream sequence
GGAATTACTGTGTGCCTACATTTGACTCTGTTAATAAGAACTGTTGAATCAAGCTTCTAATAGTATCTACTTAGAAATAGCATTCTCCTCTCTTTTAAAT
Downstream sequence
AGAGGTGAAGCCATTTTTGTAATTTTTCCAGTGTTCTCCGTATTTGGTATAATTAGAAGGGAGAGACGGAGGAGCAGTCACACACTCATATGTGAGCACA
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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