Basic Information
VIS ID
TVIS10019012
Fusion event
HBV-LOC107985242 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Host Sequence
Chromosome
chr1
Cytoband
q31.3
Reference genome
GRCh37.55
Start
194315755/194346625 (Hg38)
End
194315997/194346867 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA1K
Target gene
LOC107985242
Nearest miRNA
hsa-mir-101-1/Upstream/1210042; hsa-mir-1182/Downstream/2235546;
Nearest TSS
ENST00000473358/Upstream/197152; ENST00000435554/Downstream/4076;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/1224531, chr1-CpG: 24/Downstream/2261711
Nearby gene
LINC01031
Upstream sequence
GGCAGATGGGTTGGAATTCAAGGTCCAGTCTGTGGCTTCAAGGCGAACTCTGCTGTGCCCCTTGGCAGCATCCTCCTGGGCTACTCAGGCATCTCATTCC
Downstream sequence
CCTTTCATGCAAAAGAAACTGGAAACATTTTCTAAGTTCCAGGACACTAAACAGATTTACAGGATTGTTATATTTATAGTTTAAATTCCAAAAAGTTCTG
Target sequence
TTCTTTTATTGGCAGGCTTCTGTAGAAATATATTTCTTCTCTTTAATAACAAACTTAAAACTGGACCACTAAACAAATTTTTAGTAAACTTAGAAACTGTAGGCCATATATCTGCCTTCTGCAATTTTCCTTTCATACTCAGCTAAGTGTCAGTTATGGTTAAATTCCATCTTTAGAACCTGATAAAATTATATTTAATACCTTGACAGCCAGAAAAAAAAAAGAAAGAATTGAATTTCAAA
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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