Basic Information
VIS ID
TVIS10019022
Fusion event
HBV-chr6 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Host Sequence
Chromosome
chr6
Cytoband
q16.1
Reference genome
GRCh37.55
Start
95354151/94644433 (Hg38)
End
95354240/94644522 (Hg38)
Nearest miRNA
hsa-mir-10398/Upstream/3122696; hsa-mir-1202/Downstream/3380009;
Nearest TSS
ENST00000381078/Upstream/480513; ENST00000369293/Downstream/932928;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/1224474, chr6-CpG: 69/Downstream/932843
Nearby gene
MANEA-DT
Upstream sequence
TTTTGGAGAAAATTGGGAAGTCAGGCTTAGGTAGAGGGTGGTGTGTTTGGAGGGGATAAAATATTTTGTGCACCTGTAGTTTGTGTATTCCACCTGTGGT
Downstream sequence
CCAAGAGTTATTTTCCTATTCTCTTCCTAAGGGTAGTACCAACAACACTCATGTACACTCTTAATTATAGACATATTCATAATTAACATATTCATTTAAT
Target sequence
GGAGGCACTGGGAGAGCATATAAAGCAAGAACATGACAACTGGATGATGACCCTTCATAAAAAAGGCACTTTAGTGTCAGGAAATCTGT
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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