CAT _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10019030
Fusion event
HBV-CAT integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Host Sequence
Chromosome
chr11
Cytoband
p13
Reference genome
GRCh37.55
Start
34470736/34449189 (Hg38)
End
34470910/34449363 (Hg38)
Location type
Intron1
Fragile sites / regions
FRA11E
Target gene
CAT
miRNAs that regulate target gene
hsa-mir-30b-5p ; hsa-mir-155-5p ; hsa-mir-30a-5p ; hsa-mir-181b-5p
Nearest miRNA
hsa-mir-210/Upstream/5971641; hsa-let-7a-2/Downstream/492474;
Nearest TSS
ENST00000527297/Upstream/10264; ENST00000528104/Downstream/6786;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/9879, chr11-CpG: 98/Downstream/466418
Nearest cancer related gene
CAT(TSG, No orient, 0)
Upstream sequence
AAGACTTATTTTTAAGGACTATTAGCAACCAAAGAGATAACTAGGAGCTGGCATTCAGGAAAAATCAATACAGGAATTGAATTTGGCCTAGGGTTTTCAG
Downstream sequence
GTAAGTGCTGTGTTTATTTGCTGTAAAAAGATTGTTTCACAGCACCTGGGTCAAGTGTTATTTCCCAAAGGATTGGAAGACCTTTAACACAAGTGTCAAA
Target sequence
AGAAAGCTGATGTCCTGACCACTGGAGCTGGTAACCCAGTAGGAGACAAACTTAATGTTATTACAGTAGGGCCCCGTGGGCCCCTTCTTGTTCAGGATGTGGTTTTCACTGATGAAATGGCTCATTTTGACCGAGAGAGAATTCCTGAGAGAGTTGTGCATGCTAAAGGAGCAG
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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