VISDB Viral Integration Site DataBase

VIS ID

TVIS10019033

Fusion event

HBV-TTLL5 integration

Validated

No

Detection method

VirusFinder

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Good

Reported year

2017

PubMed ID

Virus name

HBV

Reference genome

Chromosome

chr14

Cytoband

q24.3

Reference genome

Start

End

76151847/75685504 (Hg38)

Location type

Intron5

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-4668-5p ; hsa-mir-3148 ; hsa-mir-3121-3p ; hsa-mir-548c-3p ; hsa-mir-143-5p ; hsa-mir-3944-5p ; hsa-mir-107 ; hsa-mir-103a-3p ; hsa-mir-7157-3p ; hsa-mir-5008-3p ; hsa-mir-6737-3p ; hsa-mir-6889-3p ; hsa-mir-545-5p ; hsa-mir-7845-5p ; hsa-mir-6838-5p ; hsa-mir-497-5p ; hsa-mir-424-5p ; hsa-mir-195-5p ; hsa-mir-16-5p ; hsa-mir-15b-5p ; hsa-mir-15a-5p ; hsa-mir-4475

Nearest miRNA

hsa-mir-208a/Upstream/1204643; hsa-mir-1185-1/Downstream/1580714;

Nearest TSS

Nearest CpG islands

None/Target, chr14-CpG: 35/Upstream/23276, chr14-CpG: 76/Downstream/296776

Upstream sequence

ttatttcctcaaaattttttttctgcatgtctctgcaacttctctccttttagggacgcgttacatgcctataaagcttcttataattgtctcacagctc

Downstream sequence

gatatatagtttccccaaattattctaggatgtaccaagcaaagaagtttgaaaaccactgATGTGGGGCATCTGTAGGAGAGTGCATTCTTTTTCTTAG

Target sequence

ctggcatgctgggaatgttctatacagaacttgagtggtggctacacagttgtgttcactttgtaaaaattcattatgccctgccgtgttctttgtatacttttctgtacatacgttaacttcattaaaaagcatattttaaaaaGTGaaaattttactgacagagcttttcctttaataacattttaaaaatgaggtattgaatcttgatgttgtttaggttcccttcaatatacttaaaagtgtggtgttggc