Fusion event
HBV-CES1 integration
Detection method
VirusFinder
Disease
Hepatocellular carcinoma (HCC)
End
55844838/55810926 (Hg38)
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-1225/Upstream/5068139; hsa-mir-11401/Downstream/434594;
Upstream sequence
ATCTCAAGGGAGGAGTTATCTGGTCCAGAAAGGGGATCGTGACCTTTCCCCAGATTGGGACAGGGAGTGGGACTGTGATATTCTCTTAGCTGCAGGGTAC
Downstream sequence
AACAAGGGGATAGGACTTCCACAGGAGTGACATGGCTGTCTTCTGGTCCAGTTGCCCTTCGGAGAGTGGATAGCTCATCAACTGCTAAAAAAAAAAAAAA
Target sequence
CTCTGTGGTTCCGGGCCACAATCACAGATGGGACACCAAACATCACATCTGCTATCAAGTCCAGGAACAGGTCTTTCTTTTTGACAGTGTCGTCTGTTCCTCCTAAGTATTTCTCAGTGGCTTCTGGAATCAGTTCCTTAGCAATGCACTGAAATAGATCAAAAAGTGACCACCAGCCCCGGGTGAGCGATGCAGCTTCTCCAGCCCACCAGAAAGTCCTGCCTCAATGGTGAACCCCATAAGCCCTGTGCAACT
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.